Fraunhofer Institute for Digital Medicine MEVIS
Fraunhofer Institute for Digital Medicine MEVIS

Prof. Dr. rer. nat. Matthias Günther

  • Physicist
  • Research Scientist
  • Medical Imaging
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2024

Buck MA, Eickel K, Günther M (2024) Development of a robust velocity selective arterial spin labeling sequence to address B0- and B1-field inhomogeneities for breast imaging. Magn Reson Mater Phy 37(S1):1–781(P412)
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Buck MA, Sommer L, Huber J, Günther M, Hoinkiss DC (2024) Finding the optimal acquisition strategy to visualize liver perfusion using velocity selective arterial spin labeling. Proceedings of the 40th Annual Scientific Meeting of the European Society of Magnetic Resonance in Medicine and Biology. Barcelona, Spain, 411
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Cetin A, Turhan G, Padrela B, Mahroo A, Konstandin S, Hoinkiss DC, Breutigam NJ, Keil V, Ayca ED, Özduman K, Eickel K, Mutsaerts H, Petr J, Günther M, Dincer A, Ozturk-Isik E (2024) Quantification of BBB Permeability in glioma using ASL with tissue specific T2 values. Proceedings of the ISMRM & ISMRT Annual Meeting & Exhibition. 3862
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Cetin AI, Turhan G, Padrela BE, Mahroo A, Konstandin S, Honkiss DC, Breutigam N-J, Keil V, Barkhof F, Danyeli AE, Özduman K, Necmettin Pamir MN, Eickel K, Mutsaerts H-J, Petr J, Günther M, Dincer A, Ozturk-Isik E (2024) Tissue-specific T2 BBB-ASL in Meningiomas. Magn Reson Mater Phy 37(S1):1–781(P416)
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Lütjen T, Huber J, Günther M, Hoinkiss DC (2024) Field-map-based off-resonance correction in 3D GRASE PROPELLER XD-GRASP. Proceedings of the 40th Annual Scientific Meeting of the European Society of Magnetic Resonance in Medicine and Biology. Barcelona, Spain, 221
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Mahroo A, Konstandin S, Günther M (2024) Blood–Brain Barrier Permeability to Water Measured Using Multiple Echo Time Arterial Spin Labeling<scp>MRI</scp>in the Aging Human Brain. Magnetic Resonance Imaging 59(4):1269–1282
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Morgan CA, Thomas DL, Shao X, Mahroo A, Manson TJ, Suresh V, Jansson D, Ohene Y, Günther M, Wang DJJ, Tippett LJ, Dragunow M (2024) Measurement of blood–brain barrier water exchange rate using diffusion-prepared and multi-echo arterial spin labelling: Comparison of quantitative values and age dependence. NMR In Biomed
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Nagtegaal M, Hoinkiss DC, Konstandin S, Smink J, Oeltzschner G, Günther M, van Osch M (2024) Advanced vendor-neutral MR sequences on Philips via gammaSTAR: pCASL and MRS-STEAM. Proceedings of the 40th Annual Scientific Meeting of the European Society of Magnetic Resonance in Medicine and Biology. Barcelona, Spain, 116
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Padrela B, Mahroo A, Tee M, Sneve MH, Moyaert P, Geier O, Kuijer JPA, Beun S, Nordhøy W, Zhu YD, Buck MA, Hoinkiss DC, Konstandin S, Huber J, Wiersinga J, Rikken R, de Leeuw D, Grydeland H, Tippett L, Cawston EE, Ozturk-Isik E, Linn J, Brandt M, Tijms BM, van de Giessen EM, Muller M, Fjell A, Walhovd K, Bjørnerud A, Pålhaugen L, Selnes P, Clement P, Achten E, Anazodo U, Barkhof F, Hilal S, Fladby T, Eickel K, Morgan C, Thomas DL, Petr J, Günther M, Mutsaerts HJMM (2024) Developing blood-brain barrier arterial spin labelling as a non-invasive early biomarker of Alzheimer’s disease (DEBBIE-AD): a prospective observational multicohort study protocol. BMJ Open 14(3):e081635
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Pizzini FB, Boscolo Galazzo I, Natale V, Ribaldi F, Scheffler M, Caranci F, Lovblad K-O, Menegaz G, Frisoni GB, Gunther M (2024) Insights into single-timepoint ASL hemodynamics: what visual assessment and spatial coefficient of variation can tell. Radiol med 129(3):467–477
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Joerg Matthias Günther

Degrees

  • Dr. rer. nat (magna cum laude, Heidelberg University)
  • Physics Diploma (Heidelberg University)
  • Postgraduate Education Medical Physics (Heidelberg University)
  • Prediploma Economic Sciences (Fernuni Hagen)

 

Scientific Career

03/2016 – 12/2018

Guest Scientist at the University of California, Berkeley, USA

11/2009 – current

Professor of MR-Physics, University of Bremen

11/2009 – current

Head of MR-Imaging, Fraunhofer MEVIS, Bremen

 

Member of Management Board, Fraunhofer MEVIS, Bremen

11/2008

Habilitation: "Non-invasive quantitative perfusion measurement in MRI: Efficient preparation and readout strategies for arterial spin labeling ", Faculty Physics, Heidelberg University

07/2004 – current

Executive Director of mediri GmbH, Heidelberg, Deutschland

07/2004 – 10/2009

Group Leader at the Neurological Clinic, University Clinic Mannheim, Heidelberg University,  Germany

02/2001 – 07/2004

Senior Scientist at Advanced MRI Technologies, LLC, Sebastopol, CA, USA

11/1999 – 11/2000

Postdoc at Deutsches Krebsforschungszentrum (German Cancer Research Center),  Heidelberg,  Germany

11/1996 – 11/1999

Doctoral Dissertation: Nicht-invasive Perfusionsmessung mit arterieller Spin-Markierung (german) at Deutsches Krebsforschungszentrum (German Cancer Research Center), Heidelberg,  Germany

08/1996 – 11/1996

Scientific Assistant at Max-Planck-Institute for Nuclear Physics, Heidelberg

08/1995 – 08/1996

Diploma, Heidelberg-Moscow ββ-Experiment am LNGS, Assergi, Italy for the Max-Planck-Institute, Heidelberg,  Germany

10/1991 – 08/1996

Studies of Physics at  Heidelberg University, Germany

 

11/1996 – 11/1999

Teaching Assistant, Physics for Medical classes, Heidelberg University, Heidelberg, Germany

11/1999 – 11/2000

Supervision of graduates and postgraduates at Deutsches Krebsforschungszentrum (German Cancer Research Center), Heidelberg, Germany

1998 – present

Numerous invited teaching courses at universities and laboratories world-wide (~150)

WS 2006/2007

Lecture on “Physical Basics of Medical Imaging” at Heidelberg University, Germany

09/2006

Organizer and tutor of ESMRMB-course “MR lectures on Flow and Perfusion”, Copenhagen, Denmark.

11/2006 – present

Supervision of graduates and postgraduates at Neurological clinic, University hospital Mannheim, Heidelberg University, Germany

05/2007

Lecture on Arterial Spin Labeling at the Joint Meeting of ISMRM and ESMRMB, Berlin, Germany.

10/2007

Organizer and tutor of ESMRMB-course “MR lectures on Perfusion”, Freiburg, Germany.

WS 2007/2008

Lecture on “Physical Basics of Ultrasound Imaging” at MaReCuM, Heidelberg University, Germany

WS 2008/2009

Lecture on “Physical Basics of Ultrasound Imaging” at MaReCuM, Heidelberg University, Germany

SS 2010 - 2015, 2017 - 2020

Lecture on “Physical Basics of Medical Imaging” at University Bremen, Germany

WS 2010/2011

Lecture on “MR-Physics” at University Bremen, Germany

05/2011

Lecture on Arterial Spin Labeling at the annual Meeting of ISMRM, Montreal, Canada.

05/2011

Lecture on Perfusion at the annual Meeting of ISMRM, Montreal, Canada.

SS 2011 - 2012

Lecture on “Physik für Biologen” at University Bremen, Germany

SS 2011 - 2015, 2017 -2020

Lecture on “Experimentalphysik VI: Kerne und Teilchen” at University Bremen, Germany

09/2011

Organizer and tutor of ESMRMB-course “MR lectures on Perfusion”, Oxford, UK.

WS 2011/2012, 2015/2016

Lecture series on “Methoden der Biophysik” at University Bremen, Germany

05/2013

Tutor of “Arterial Spin Labeling for physicians” in Verona, Italy

09/2013

Organizer and tutor of “Arterial Spin Labeling for physicists” in Toulouse, France

06/2017

Organizer and tutor of ESMRMB-course “Lectures on MR - Measurement of perfusion and capillary exchange”, Bremen, Germany

09/2018

Organizer and tutor of ESMRMB-course “Lectures on MR - MR image processing - from image data to information”, Berlin, Germany

Patents

Translucent Intensity Projection Imaging
Inventors: Oshio, K.; Guenther, M.; Feinberg, D.A.           
Filing date: 05/22/2001  
US 7020318

Susceptibility Correction and Contrast Encoding with Simultaneously Refocused MR Images
Inventors: Guenther, M.; Feinberg, D.A; Oshio, K.             
Filing date: 05/16/2002                                                                                       
WO/2003/098233

Method and Apparatus for Removing Specific Stimulated Echoes in Simultaneous Image Refocusing
Inventors: Guenther, M.; D. A. Feinberg, D.A.                   
Filing date: 06/15/2002  
US 6853188

Efficient Visualization of Cortical Vascular Territories by Cycled Arterial Spin Labeling MRI
Inventors: Guenther, M.                                                   
Filing date: 05/20/2005                                                                                       
WO/2006/127687

Extreme Speed-Up Of Acquisition Of Perfusion Time Series By Cycled Arterial Spin Labeling MRI
Inventors: Guenther, M.                                                   
Filing date: 09/19/2006                                                                                       
WO/2007/035824

3D motion detection and correction by object tracking in ultrasound images
Inventors: Guenther, M., Bongers, A.                                
Filing date: 6/29/2009              
WO 2010037436 A1

Verfahren und Vorrichtung zur Ermittlung von T2 und T2* mittels MRT
Inventors: Guenther, M., Gregori, J.                                  
Filing date: 04/02/2009                                                                                       
WO2010112215 A1

Ultraschall-Messeinrichtung, Untersuchungsgerät und Verfahren zu deren Betrieb
Inventors: Tretbar, S; Degel, C; Günther, M                       
Filing date: 12/5/2012                                                                                       
PCT/EP2013/000470

ASL MRI using a sequence of magnetically labeled or unlabeled fluid boli
Inventors: von Samson-Himmelstjerna, F.; Günther, M       
Filing date: 03/27/2014             
WO 2015144768 A1

Imaging system for generating a series of image
Inventors: Braeutigam, N; von Samson-Himmelstjerna, F.; Günther, M,                                                                                     
Filing date: 4/20/2016,                                                                                       
WO002017182575A1

System, method and computer program for magnetic resonance scanners: Calculation flow
Inventors: Cordes, C.; Porter, D.; Archipovas, S.; Günther, M.
Filing date: 4/20/2016,                                                                                      
WO002017182579A1

Rekonstruktion von Ultraschalldaten mittels neuronaler Netzwerke    
Inventor: Günther, M.                                                     
Filing date: 11/09/2017                                                                                      
PCT/EP2018/080495

Magnetic resonance imaging system                                             
Inventor: Günther, M.                                                     
Filing date: 05/03/2018  
DE 10 2018 110 826.5

Cable Mantle/Jacket for shield current suppression
Inventor: Betancourt, D; Bertuch, T; Jenne,J; Günther, M.  
Filing date: 11/29/2019     
submitted

 

Reviewer for

(selection, since 2001):

European Commission, COST organization, European Research Council, Deutsche Forschungsgemeinschaft (DFG), Schweizer Nationalfond (SNF), Alexander von Humboldt-Stiftung, Deutscher Akademischer Auslandsdienst (DAAD),Research Promotion Foundation (RPF) of Cyprus, Poland - National Centre for Research and Development

Magnetic Resonance in Medicine, IEEE Transaction for Medical Imaging, Cerebrovascular Diseases, Journal of Magnetic Resonance Imaging, Journal of Neuroscience Methods, Journal of Neuroimaging, Journal of Neurology, Neurosurgery & Psychiatry, Kidney International, Zeitschrift für Medizinische Physik, Magnetic Resonance Materials in Physics Biology and Medicine, NeuroImage, Neuroradiodiology, Biomedical Signal Processing and Control, Applied Sciences, IPMI, MICCAI, ISMRM, ESMRMB