Artificial intelligence and computer-aided support for diagnosis and therapy in digital medicine—these are the topics the Fraunhofer Institute for Digital Medicine MEVIS is presenting at the SPIE Medical Imaging conference, which is held in San Diego/USA from February 16 to 20. This year, Fraunhofer MEVIS is again well represented at the renowned conference with numerous scientific and educational contributions, including a live demonstration workshop, two training courses, three oral and six poster presentations.